Cpe1786 is a good candidate to participate in cysteine-dependent regulation of iron-sulfur clusters biogenesis but maybe also of some steps of fermentation pathways. This deserves further investigations. Acknowledgements We are grateful to A. Danchin O. Soutourina and M. Popoff for stimulating discussions. We thank A. Antunes and E. Camiade for their help and P. Courtin for metabolite analysis. I. M.-V. and E. H. are full professor and ATER at the Université

Paris 7, respectively. Research was supported by grants from the Centre National de la Recherche Scientifique (CNRS URA 2171) and the Institut Pasteur (PTR N°256). G. A was the recipient of a grant from the Ministère de l’enseignement supérieur et de la recherche and from the Pasteur-Weizmann foundation. Idasanutlin purchase References 1. Ayala-Castro C, Saini A, Outten FW: Fe-S cluster assembly pathways in bacteria. Selleckchem BAY 63-2521 Microbiol Mol Biol Rev 2008,72(1):110–125.PubMedCrossRef 2. Masip L, Veeravalli K, Georgiou G: The many faces of glutathione in bacteria. ARS-1620 mw Antioxid Redox Signal 2006,8(5–6):753–762.PubMedCrossRef

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