The guideline focuses on evidence underpinning four main areas: the diagnosis of JIA, treatment and management of JIA in the early stage, during acute episodes, and the long term management of JIA. It covers issues such as early and accurate diagnosis, care and referral pathways, use of medications, non-pharmacological management including evidence for land and water exercise, patient self-management education, and psychosocial support requirements. Two

detailed algorithms are presented on pages 8 and 9, covering the diagnosis Birinapant clinical trial and early management of JIA, and the management of JIA. A summary of the 21 recommendations is presented on pages 10–11, with more detailed explanation of the recommendation level and

specific evidence contained in pages 12–24. Three pages of resources are provided on pages 35–37 including publications, electronic sources (websites), and a history and clinical examination checklist to assist with examination and differential diagnosis. “
“Latest update: May 2010. Date of next update: 2014. Patient group: Individuals with chronic obstructive pulmonary disease (COPD). Intended audience: Health professionals who manage patients with COPD. Additional versions: This is the first update to the guidelines. The original guidelines were published in the Medical Journal of Australia in 2003. Caspase activity (http://www.mja.com.au/public/issues/178_06_170303/tho10508_all.html). Expert working group: The guidelines were developed by the Australian Lung Foundation and the Thoracic Society of Australia and New Zealand. The guidelines evaluation committee consisted of 8 Australian health professionals

representing medicine, public health, and physiotherapy. A larger group of 27 experts from Australia and New Zealand including physiotherapists ADAMTS5 also contributed. Funded by: Australian Lung Foundation. Consultation with: Draft versions of the guidelines were available on the RACGP website for public consultation and over 200 stakeholder groups were specifically targeted. Approved by: The Royal Australian College of Physicians, The Royal College of Nursing Australia, the Australian Physiotherapy Association, Australian Asthma and Respiratory Educators Association, and the Asthma Foundation. Location: The website (http://www.copdx.org.au/home) contains the guidelines spread over pages on the site, as well as a .pdf version. Description: The .pdf version is a 71-page document that presents recommendations and the underlying evidence to assist with the diagnosis and management of patients with COPD. The key recommendations are summarised on page 10 in the COPD-X plan: Confirm diagnosis, Optimise function, Prevent deterioration, Develop a self-management plan, and manage eXacerbations.