The present study aimed to evaluate the safety and validity of endoscopic hemostasis for lower gastrointestinal bleeding in elderly individuals aged more than 70 years. Methods: We reviewed the cases of 36 patients with lower gastrointestinal bleeding who underwent endoscopic hemostasis at our hospital between April 2009 and February 2014. Results: The mean age was 76.2 years (70–91 years). Nineteen patients were men, and 17 were women. Five patients

were using an antiplatelet Peptide 17 mouse agent. Seven patients were using an anticoagulant agent (including heparin injection). Three patients were using a combination of both agents. The cause of bleeding was ulcer induced by endoscopic mucosal resection in 12 cases, ulcer induced by endoscopic submucosal dissection in 6, anastomosis site of colon resection in 5, colon diverticulum in 4, radiation proctitis in 4, hemorrhagic rectal ulcer in 3, biopsy for advanced colorectal cancer in 1, and vascular ectasia in 1. The methods of treatment were as follows:

clipping in 27 cases, argon plasma coagulation in 6, hemostatic forceps in 5, and temporary snare in 1. All patients Obeticholic Acid who underwent endoscopic therapy achieved hemostasis. There were no serious complications such as perioperative death or complications requiring emergency surgery. Conclusion: Endoscopic hemostasis is a safe and effective treatment for lower gastrointestinal bleeding in the elderly. Key Word(s): 1. lower gastrointestinal bleeding endoscopic therapy Presenting Author: YULI PRAMANA TRIYANTA Additional Authors: Na Corresponding Author: YULI PRAMANA TRIYANTA Affiliations: PGI PEGI Objective: Endoscopic schlerotherapy and endoscopic ligation were accepted in the treatment of esophageal varices bleeding in patients with liver cirrhosis. Endoscopic ligation seem to be superior than endoscopic schlerotherapy. Primary prevention must be performed if the criteria are concluded, and the secondary prevention must be

performed to prevent variceal rebleeding. According to the guideline Endoscopic ligation is the first choice, if ligation was difficult because of continued bleeding or this technique is not available, endoscopic variceal sclerotherapy should be performed. Methods: Cases report. Case 1. A women get serial variceal ligation. Ponatinib At the last endoscopic evaluation, there was esophageal varices lining between cicatrix, it is difficult to perform ligation, so schlerotherapy must be choosed. Case 2. A man with liver cirrhosis and the shape of the varix is wide and look like a fan, schlerotherapy was done. Case 3. A man with liver cirrhosis and has esophageal varices continue to the gastroesophageal varices, it’s better schlerotherapy. Results: Beside variceal size and tension of variceal wall, others condition of varix itself must be mentioned. The type of esophageal varix is important. The varix look like pipe, it’s better to perform ligation.