This article is part of the Special Issue entitled ‘Neurodevelopmental Disorders’. (c) 2012 Elsevier Ltd. All rights reserved.”
“Improving patient adherence to antidepressant treatment is an important issue. Patients’ attitudes toward symptoms, results, causes, disease course, and effective treatment of depression can influence their adherence to therapy. We aimed to assess the efficacy of an educational leaflet designed to improve patients’ attitudes toward depression and antidepressant treatment. Participants were one hundred twenty-two outpatients of three psychiatric clinics in Japan who met the DSM-IV criteria for depression. Patients in the intervention group received an educational leaflet Flavopiridol solubility dmso at the start
of the study. Participants filled in The Antidepressant Compliance Questionnaire (ADCQ) and Beck Depression Inventory (BDI) before and after the intervention. Intervention group showed
greater improvements on the total score of ADCQ the score on the “”positive beliefs regarding antidepressants”" subscale. They maintained the scores on the “”perceived doctor-patient relationship”" subscale, where the control group lowered those scores. No significant difference in improvement in BDI scores was observed between groups. learn more The intervention using an educational leaflet had a significant positive impact on patients’ attitudes toward depression and antidepressant treatment. Our results indicate that the educational leaflet is an effective tool for enhancement of face-to-face education by medical buy GSK461364 professionals. Trial registration UMIN000002981, www.umin.ac.jp/ctr/index.htm. (C) 2010 Elsevier Ireland Ltd. All rights reserved.”
“Airborne viruses are expected to be ubiquitous in the atmosphere but they still remain poorly understood. This study investigated the temporal and spatial dynamics of airborne viruses and their genotypic characteristics in air samples collected from three distinct land use types (a residential district [RD], a forest [FR], and an industrial complex
[IC]) and from rainwater samples freshly precipitated at the RD site (RD-rain). Viral abundance exhibited a seasonal fluctuation in the range between 1.7 x 10(6) and 4.0 X 10(7) viruses m(-3), which increased from autumn to winter and decreased toward spring, but no significant spatial differences were observed. Temporal variations in viral abundance were inversely correlated with seasonal changes in temperature and absolute humidity. Metagenomic analysis of air viromes amplified by rolling-circle phi29 polymerase-based random hexamer priming indicated the dominance of plant-associated single-stranded DNA (ssDNA) geminivirus-related viruses, followed by animal-infecting circovirus-related sequences, with low numbers of nanoviruses and microphages-related genomes. Particularly, the majority of the geminivirus-related viruses were closely related to ssDNA mycoviruses that infect plant-pathogenic fungi.