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expression of multiple chemoresistance genes. Cancer Res 1999, 59:3505–3511.PubMed Competing interests The authors declare no competing financial interests. Authors’ contributions YG, KY, and QQ were involved in the design of the study, performance of the experiments, data analysis, and manuscript writing. JF and MZ participated in the experimental design and data analysis. FC conceived of the study, and was involved in financial support, the design of the study, data analysis, and final approval of the manuscript. All the authors read and approved the manuscript.”
“Background Elevated GH and IGF-I levels are major causes of morbidity and mortality in patients with acromegaly [1, 2]. The mainstay of treatment involves surgical resection of the somatotrophic adenoma causing the disease. In experienced hands, it is associated with cure rates of 50-70%, depending on the size, morphology, and location of the tumor.